Fulminant hepatic failure in primary dengue infection.

نویسندگان

  • A M Vijayalakshmi
  • S Devaprasath
چکیده

A 9-month-old child presented with four days fever and altered sensorium for 2 days. He developed seizures in the emergency department and was in a state of shock. His blood sugar was 9 mg/dL. He was resuscitated with intravenous fluids. The child had fever, altered sensorium and erythematous skin. His liver was palpable 4 cm below right costal margin and spleen was just palpable. The limbs were spastic and deep tender reflexes were brisk. His initial blood count showed a total count of 23.1 × 103/μL, hematocrit of 33%, platelet count of 22,000/μL. His liver function test were SGPT of 5907 U/L, SGOT of 20,480 U/L and serum bilirubin of 2.7 mg/dL. His prothrombin time was prolonged(68s). Serology for hepatitis A, C and E, and HBs Ag were negative. Imaging showed right sided pleural effusion and moderate ascites. Dengue IgM antibodies were positive and dengue IgG was negative, suggestive of primary dengue infection. He developed progressive jaundice with the maximum bilirubin level of 22.9 mg/ dL, which resolved completely 8 weeks after onset.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fatal Fulminant Hepatic Failure in a Diabetic with Primary Dengue

We report a 49-year-old diabetic with dengue hemorrhagic fever who developed fulminant hepatitis, severe coagulopathy, shock, and refractory metabolic acidosis and died on the eighth day of illness. This is the only second report of an adult with fatal fulminant hepatic failure due to dengue, and the first case arising from a primary dengue infection.

متن کامل

Is dengue emerging as important cause of acute liver failure in endemic regions?

Dengue virus infection continues to be major public health problem in large part of world. The epidemiology of dengue viral infection is becoming increasingly complex and has substantially changed over almost past six decades not only in terms of prevalent strains and geographical locations but also in terms of disease severity and atypical presentations. Though liver is the most common organ a...

متن کامل

Glyphosate Poisoning with Acute Fulminant Hepatic Failure

Background: Glyphosate containing herbicides are widely used the world over. They are marketed as nontoxic to humans, but numerous studies have showed that these glyphosate-based herbicides (GlySH) can cause multiorgan damage.1 Recent reports of animal studies on rats have raised a doubt of liver damage after long term exposure to GlySH. Case Presentation: a young male had chronic exposure to G...

متن کامل

Fulminant hepatic failure in children and adolescents in Northern Brazil.

The histological findings of fulminant hepatic failure were correlated to the demographic, clinical, biochemical and virological features in children and adolescents, native to the Amazonas State in Northern Brazil. 96.2% had evidence of infection by primary hepatotrophic viruses. Histological analysis revealed three distinct patterns of fulminant hepatic failure.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Indian pediatrics

دوره 47 3  شماره 

صفحات  -

تاریخ انتشار 2010